Medical Researches
Possibly Effective
Based on 9 Researches
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
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Magnesium therapy aids back painA double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
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We explored a study that investigated the effects of zinc supplementation on bone density in individuals with beta-thalassaemia and its potential influence on back pain. The research did not specifically isolate the impact of zinc on back pain, which makes it challenging to draw definitive conclusions about its effectiveness for this particular issue.
While the study showed significant increases in bone mineral density at the lumbar spine after 12 and 18 months of zinc treatment, it did not provide detailed information regarding any changes in back pain associated with these improvements.
There was also no mention of fractures related to back pain reduction, nor were adverse effects reported in the zinc supplementation trial. Thus, it leaves us with the understanding that, while zinc may help with bone density, its direct impact on alleviating back pain remains unclear. Further research would be necessary to clarify any connections.
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Calcium aids in back pain reliefRegular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
Calcium's effects unclear in isolation
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
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Magnesium shows promise for IVDDROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Moderate relevance to magnesium treatment
We explored the potential of magnesium-containing microspheres to help manage intervertebral disc degeneration (IVDD), a condition often linked with back pain. This innovative treatment focuses on using microspheres that respond to reactive oxygen species, which are indicators of oxidative stress often seen in IVDD. By targeting these harmful agents, we aimed to reduce the associated inflammation and pain.
The microspheres, composed of a polymer shell and a magnesium core, work by releasing hydrogen gas in response to oxidative conditions, which can help neutralize damaging free radicals in the body. We observed significant improvements in a rat model of disc degeneration, which included less damage to the disc structure, reduced cell death, and overall better disc health.
The results of this study highlight magnesium's role as a key component in enhancing the antioxidative capacity of the treatment. This not only mitigates the effects of IVDD but also supports the idea that antioxidant therapies may hold promise for alleviating back pain. Importantly, we noted that this approach showed strong biocompatibility and minimal toxicity, making it a potential option for future clinical applications.
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